Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.51 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20340621 | 0.85 | MCL1 (0.52) | TDO2RAD51IDO1LRRK2CYP2A6 | |
| SCHEMBL17517554 | 0.85 | TDO2 (0.48) | TDO2RAD51IDO1LRRK2CYP2A6 | |
| SCHEMBL17102969 | 0.82 | MAOA (0.51) | TDO2RAD51CYP11B2TBXAS1MCL1 | |
| SCHEMBL17102971 | 0.81 | MAOA (0.53) | TDO2RAD51CYP11B2TBXAS1MCL1 | |
| SCHEMBL27905858 | 0.75 | GBA1 (0.44) | TDO2CYP2A6CYP11B2TBXAS1 | |
| SCHEMBL17517530 | 0.74 | TDO2 (0.39) | TDO2RAD51CYP2A6CYP11B2CYP3A4 | |
| SCHEMBL17517529 | 0.74 | TDO2 (0.39) | TDO2RAD51CYP2A6CYP11B2CYP3A4 | |
| SCHEMBL20340618 | 0.72 | MCL1 (0.42) | ALDH1A1MCL1 | |
| SCHEMBL29773852 | 0.71 | CYP11B2 (0.55) | TDO2RAD51IDO1LRRK2CYP2A6 | |
| SCHEMBL12215977 | 0.71 | TDO2 (0.55) | TDO2IDO1LRRK2CYP2A6CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10011614-B2 | Bis-β-carboline compound and preparation method, pharmaceutical composition and use thereof | XINJIANG HUASHIDAN PHARMACEUTICAL RESEARCH CO., LTD (CN) | 2018-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10011614-B2 | Bis-β-carboline compound and preparation method, pharmaceutical composition and use thereof | BRCA1, CA7, DCK | TDO2 3274/4885RAD51 1934/4885IDO1 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.