Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 5/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12539335 | 0.80 | RAB9A (0.43) | KIF11KCNH2LTA4HSLC6A1SLC6A11 | |
| SCHEMBL2029074 | 0.80 | MAOB (0.49) | KIF11KCNH2LTA4HRAB9ATP53 | |
| SCHEMBL28241152 | 0.79 | LTA4H (0.52) | KIF11KCNH2LTA4HSLC6A1SLC6A11 | |
| SCHEMBL16624711 | 0.79 | GABRA1 (0.48) | MIFKIF11KCNH2LTA4HSLC6A1 | |
| Hydrochloric Acid SCHEMBL30186367 | 0.78 | LTA4H (0.50) | KIF11KCNH2LTA4HSLC6A1SLC6A11 | |
| SCHEMBL16624613 | 0.78 | MAOB (0.52) | CYP3A4HPGDLTA4HRAB9ATP53 | |
| SCHEMBL12539760 | 0.77 | ACP1 (0.45) | ALDH1A1LTA4HRAB9ATP53PKM | |
| SCHEMBL3982356 | 0.77 | ACP1 (0.45) | ALDH1A1LTA4HRAB9ATP53PKM | |
| 3-Methoxybenxyl Isothiocyanate SCHEMBL1551644 | 0.74 | MIF (0.64) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL16631068 | 0.72 | MAOB (0.47) | RAB9ATP53PKMNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511260-B1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | UNIV GIFU (JP) | 2015-07-29 | — | — | EP | disclosed |
| EP-2511260-B1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | UNIV GIFU (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-8633304-B2 | Oligonucleotide derivative comprising an aromatic compound | GIFU UNIVERSITY (JP) | 2014-01-21 | — | — | US | disclosed |
| US-8633304-B2 | Oligonucleotide derivative comprising an aromatic compound | GIFU UNIVERSITY (JP) | 2014-01-21 | — | — | US | disclosed |
| US-8633304-B2 | Oligonucleotide derivative comprising an aromatic compound | GIFU UNIVERSITY (JP) | 2014-01-21 | — | — | US | disclosed |
| EP-2511260-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | Gifu University (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-20120245341-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | GIFU UNIVERSITY (JP) | 2012-09-27 | — | — | US | disclosed |
| US-20120245341-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | GIFU UNIVERSITY (JP) | 2012-09-27 | — | — | US | disclosed |
| WO-2011071078-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | 国立大学法人岐阜大学 (JP) | 2011-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245341-A1 | AROMATIC COMPOUND, MODIFICATION CARRIER THAT USES SAME AND IS USED FOR SYNTHESIZING AN OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE DERIVATIVE, AND OLIGONUCLEOTIDE CONSTRUCT | NSUN2, SLCO2A1, ABCB7 | MIF 4104/4885TRPA1 421/4885ALDH1A1 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.