Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.42 |
| ▸ | CTSS | P25774 | 7/20 | 0.42 |
| ▸ | CTSB | P07858 | 6/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615855 | 0.91 | CTSL (0.36) | CTSLCTSSCTSBCTSKACACB | |
| SCHEMBL18616645 | 0.89 | CTSS (0.39) | CTSLCTSSCTSBCTSKCACNA1H | |
| SCHEMBL20335400 | 0.89 | CTSL (0.39) | CTSLCTSSCTSBCTSKCACNA1H | |
| SCHEMBL20341792 | 0.83 | CTSL (0.36) | CTSLCTSSCTSBCTSKCACNA1H | |
| SCHEMBL20341776 | 0.83 | ACACB (0.32) | CTSLCTSSCTSBACACBCACNA1H | |
| SCHEMBL23810230 | 0.83 | CTSL (0.34) | CTSLCTSSCTSBCTSKCACNA1H | |
| SCHEMBL18615916 | 0.82 | CTSL (0.37) | CTSLCTSSCTSK | |
| SCHEMBL20341846 | 0.82 | CTSL (0.37) | CTSLCTSSCTSBCTSKCACNA1H | |
| SCHEMBL18615975 | 0.82 | CTSL (0.35) | CTSLCTSSCTSBCTSKCYP2D6 | |
| SCHEMBL20341764 | 0.82 | CTSL (0.38) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |