Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14667537 | 0.83 | POLB (0.57) | POLBMAPTTDP1ALDH1A1LMNA | |
| SCHEMBL4327798 | 0.78 | KMO (0.52) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL8310029 | 0.78 | KMO (0.52) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL2171300 | 0.77 | NPC1 (0.49) | POLBALDH1A1NPC1RAB9A | |
| SCHEMBL2171294 | 0.77 | NPC1 (0.49) | POLBALDH1A1NPC1RAB9A | |
| SCHEMBL17428488 | 0.71 | PPARG (0.49) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL24704536 | 0.70 | GRIN2B (0.45) | KMOPRSS1PRSS2PRSS3PPARG | |
| SCHEMBL13754825 | 0.70 | PRSS1 (0.64) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL9526439 | 0.70 | KMO (0.55) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL407605 | 0.70 | KMO (0.67) | KMOPRSS1PRSS2PRSS3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927218-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-07-04 | — | — | EP | disclosed |