Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665627 | 0.85 | ELANE (0.61) | ALDH1A3KMT2AALDH1A1CYP2A6ELANE | |
| SCHEMBL18411205 | 0.79 | LMNA (0.55) | KMT2AALDH1A1ELANEMAPTMEN1 | |
| SCHEMBL24974009 | 0.78 | ELANE (0.47) | KMT2AALDH1A1ELANEKDM4E | |
| SCHEMBL6993301 | 0.77 | ELANE (0.53) | KMT2AALDH1A1ELANEMAPTMEN1 | |
| SCHEMBL22329039 | 0.76 | ALDH1A3 (0.45) | ALDH1A3KMT2AALDH1A1CYP2A6ELANE | |
| SCHEMBL1667621 | 0.76 | ALDH1A1 (0.57) | ALDH1A3KMT2AALDH1A1CYP2A6TYR | |
| SCHEMBL1665621 | 0.75 | ALDH1A3 (0.56) | ALDH1A3KMT2AALDH1A1CYP2A6TYR | |
| SCHEMBL203500 | 0.75 | KMT2A (0.61) | ALDH1A3KMT2AALDH1A1CYP2A6ELANE | |
| SCHEMBL25248280 | 0.75 | KMT2A (0.50) | ALDH1A3KMT2AALDH1A1CYP2A6ELANE | |
| SCHEMBL14783590 | 0.74 | KMT2A (0.62) | ALDH1A3KMT2AALDH1A1CYP2A6PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342796-A1 | SUBSTITUTED POLYESTERS BY THIOL-ENE MODIFICATION: RAPID DIVERSIFICATION FOR THERAPEUTIC PROTEIN STABILIZATION | The Regents of The University of California (US) | 2018-07-04 | — | — | EP | disclosed |