Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20344797 | 0.88 | ALDH1A1 (0.35) | CES2POLBMAPTTP53ATAD2 | |
| SCHEMBL20344756 | 0.87 | HDAC1 (0.37) | CES2POLBMAPTTP53ATAD2 | |
| SCHEMBL20344743 | 0.81 | BRD4 (0.38) | CES2POLBMAPTTP53ATAD2 | |
| SCHEMBL20344693 | 0.77 | HDAC6 (0.38) | CES2POLBMAPTTP53ATAD2 | |
| SCHEMBL20344778 | 0.76 | HDAC1 (0.39) | CES2POLBMAPTTP53ATAD2 | |
| SCHEMBL20344782 | 0.76 | HDAC6 (0.35) | CES2MAPTATAD2HDAC6HDAC1 | |
| SCHEMBL22756341 | 0.72 | ATAD2 (0.37) | CES2POLBMAPTTP53ATAD2 | |
| SCHEMBL20344775 | 0.70 | GRIN1 (0.37) | CES2POLBMAPTTP53ATAD2 | |
| SCHEMBL20344798 | 0.70 | BRD4 (0.41) | POLBMAPTTP53ATAD2BRD4 | |
| SCHEMBL436376 | 0.69 | ATAD2 (0.48) | POLBMAPTTP53ATAD2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342766-B1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3342766-A1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) | 2018-07-04 | — | — | EP | disclosed |