Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | BRD1 | O95696 | 2/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PARG | Q86W56 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20344792 | 0.88 | KDM4E (0.46) | KDM4EPOLBHSD17B10L3MBTL1MAPT | |
| SCHEMBL20344803 | 0.86 | MAPT (0.35) | POLBMAPTTP53SMN1; SMN2LMNA | |
| SCHEMBL20344771 | 0.81 | TP53 (0.39) | KDM4EPOLBHSD17B10L3MBTL1MAPT | |
| SCHEMBL20344772 | 0.79 | BRPF1 (0.42) | KDM4EPOLBHSD17B10L3MBTL1MAPT | |
| SCHEMBL20344756 | 0.73 | HDAC1 (0.37) | POLBMAPTTP53LMNAPKM | |
| SCHEMBL20344813 | 0.71 | BRPF1 (0.35) | MAPTTP53LMNABRPF1P2RX3 | |
| SCHEMBL20344728 | 0.70 | BRPF1 (0.36) | MAPTTP53BRD1BRPF1P2RX3 | |
| SCHEMBL20344753 | 0.69 | BRPF1 (0.35) | KDM4EPOLBHSD17B10L3MBTL1MAPT | |
| SCHEMBL20344791 | 0.68 | BRPF1 (0.46) | KDM4EPOLBHSD17B10L3MBTL1MAPT | |
| SCHEMBL20335474 | 0.66 | KDM4E (0.51) | KDM4EPOLBHSD17B10L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342766-B1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3342766-A1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) | 2018-07-04 | — | — | EP | disclosed |