Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BRD1 | O95696 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20344772 | 0.88 | BRPF1 (0.42) | BRPF1HDAC8HDAC1HDAC6KDM4E | |
| SCHEMBL20616477 | 0.83 | BRPF1 (0.55) | BRPF1HDAC8HDAC1HDAC6POLB | |
| SCHEMBL20344792 | 0.77 | KDM4E (0.46) | BRPF1KDM4EPOLBHSD17B10L3MBTL1 | |
| SCHEMBL20616474 | 0.77 | BRPF1 (0.47) | BRPF1HDAC8HDAC1HDAC6KDM4E | |
| SCHEMBL20344777 | 0.73 | BRPF1 (0.50) | BRPF1HDAC8HDAC1HDAC6BRD1 | |
| SCHEMBL20344771 | 0.70 | TP53 (0.39) | BRPF1KDM4EPOLBHSD17B10L3MBTL1 | |
| SCHEMBL15298954 | 0.70 | BRD4 (0.44) | BRPF1HDAC8HDAC1HDAC6KMT2A | |
| SCHEMBL20335474 | 0.69 | KDM4E (0.51) | BRPF1KDM4EPOLBHSD17B10L3MBTL1 | |
| SCHEMBL19805106 | 0.69 | BRD4 (0.42) | BRPF1HDAC8HDAC1HDAC6MAPT | |
| SCHEMBL20344752 | 0.69 | BRPF1 (0.50) | BRPF1HDAC8HDAC1HDAC6BRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10842151-B2 | Small molecule compound for enhancing plant stress resistance | CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) | 2020-11-24 | — | — | US | disclosed |
| EP-3342766-A1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) | 2018-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10842151-B2 | Small molecule compound for enhancing plant stress resistance | CYP4F11, RICTOR, MYB | BRPF1 1596/4885HDAC8 2101/4885HDAC1 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.