Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.34 |
| ▸ | BRD1 | O95696 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20344781 | 0.86 | KDM4E (0.39) | MAPTBRPF1P2RX3BRD1TP53 | |
| SCHEMBL20344813 | 0.84 | BRPF1 (0.35) | MAPTBRPF1P2RX3TP53LMNA | |
| SCHEMBL20344728 | 0.84 | BRPF1 (0.36) | MAPTBRPF1P2RX3BRD1TP53 | |
| SCHEMBL20344753 | 0.82 | BRPF1 (0.35) | MAPTBRPF1P2RX3TP53THRB | |
| SCHEMBL20344777 | 0.79 | BRPF1 (0.50) | MAPTBRPF1BRD1TP53BRD4 | |
| SCHEMBL20344792 | 0.73 | KDM4E (0.46) | MAPTBRPF1BRD1TP53PKM | |
| SCHEMBL20344756 | 0.73 | HDAC1 (0.37) | MAPTTP53BRD4PKMLMNA | |
| SCHEMBL24519726 | 0.68 | P2RX3 (0.41) | MAPTBRPF1P2RX3BRD1TP53 | |
| SCHEMBL20344757 | 0.67 | BRPF1 (0.50) | MAPTBRPF1BRD1TP53BRD4 | |
| SCHEMBL20616477 | 0.67 | BRPF1 (0.55) | MAPTBRPF1P2RX3BRD1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342766-B1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3342766-A1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) | 2018-07-04 | — | — | EP | disclosed |