Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | BRD1 | O95696 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20344781 | 0.88 | KDM4E (0.39) | KDM4EHSD17B10POLBL3MBTL1KMT2A | |
| SCHEMBL20344791 | 0.77 | BRPF1 (0.46) | KDM4EHSD17B10POLBL3MBTL1PTGDR2 | |
| SCHEMBL20344803 | 0.73 | MAPT (0.35) | POLBKMT2AMEN1MAPTLMNA | |
| SCHEMBL20344771 | 0.69 | TP53 (0.39) | KDM4EHSD17B10POLBL3MBTL1KMT2A | |
| SCHEMBL20344753 | 0.69 | BRPF1 (0.35) | KDM4EHSD17B10POLBL3MBTL1PTGDR2 | |
| SCHEMBL20335474 | 0.69 | KDM4E (0.51) | KDM4EHSD17B10POLBL3MBTL1KMT2A | |
| SCHEMBL19805120 | 0.68 | TP53 (0.44) | POLBKMT2AMEN1GAATSHR | |
| SCHEMBL19805057 | 0.68 | TP53 (0.34) | POLBKMT2AMEN1CHRNA7ALDH1A1 | |
| SCHEMBL20344772 | 0.68 | BRPF1 (0.42) | KDM4EHSD17B10POLBL3MBTL1KMT2A | |
| SCHEMBL20344728 | 0.67 | BRPF1 (0.36) | MAPTBRD1BRPF1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342766-B1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3342766-A1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) | 2018-07-04 | — | — | EP | disclosed |