Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.39 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | USP14 | P54578 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357703 | 0.81 | KDM4E (0.42) | KDM4ETP53HRH3CHRNA10CHRNA9 | |
| SCHEMBL18357674 | 0.80 | TP53 (0.49) | KDM4ETP53HRH3CHRNA10CHRNA9 | |
| SCHEMBL18357797 | 0.78 | KDM4E (0.52) | KDM4ETP53HRH3HTR7 | |
| SCHEMBL20346944 | 0.76 | KDM4E (0.53) | KDM4ETP53HRH3CHRNA10CHRNA9 | |
| SCHEMBL20345540 | 0.76 | DPP4 (0.33) | HRH3 | |
| SCHEMBL20345548 | 0.75 | HRH3 (0.40) | KDM4ETP53HRH3CHRNA10CHRNA9 | |
| SCHEMBL18357770 | 0.75 | EPHX2 (0.46) | KDM4ETP53HRH3 | |
| SCHEMBL20345543 | 0.73 | KDM1A (0.40) | KDM4ETP53KCNH2ITGAL | |
| SCHEMBL18357436 | 0.72 | TP53 (0.47) | KDM4ETP53HRH3CHRNA10CHRNA9 | |
| SCHEMBL22919201 | 0.71 | TSHR (0.64) | KDM4ETP53CHRNA10CHRNA9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186768-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186768-A1 | Antibacterial Compounds | FDPS, SQOR, NDUFS3 | KDM4E 3387/4885TP53 3030/4885HRH3 3449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.