Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357565 | 0.82 | LOXL2 (0.32) | LOXL2MAOB | |
| SCHEMBL18357788 | 0.81 | NSD2 (0.31) | LOXL2 | |
| SCHEMBL18357546 | 0.80 | ABAT (0.35) | LOXL2HSD17B10USP2CYP3A4ALDH1A1 | |
| SCHEMBL18357596 | 0.80 | LOXL2 (0.35) | LOXL2HSD17B10USP2CYP3A4ALDH1A1 | |
| SCHEMBL20345584 | 0.78 | MAOB (0.42) | LOXL2ALDH1A1MAPK1CYP1A2MAOB | |
| SCHEMBL20346945 | 0.76 | RORC (0.46) | DPP4HSD17B10RORC | |
| SCHEMBL20345541 | 0.76 | KDM4E (0.41) | HRH3 | |
| SCHEMBL18357434 | 0.75 | LOXL2 (0.41) | LOXL2HSD17B10USP2CYP3A4ALDH1A1 | |
| SCHEMBL18357603 | 0.75 | MAOB (0.45) | LOXL2MAOB | |
| SCHEMBL18357392 | 0.75 | ST14 (0.38) | LOXL2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186768-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186768-A1 | Antibacterial Compounds | FDPS, SQOR, NDUFS3 | DPP4 108/4885LOXL2 4199/4885HSD17B10 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.