SCHEMBL20348686

SCHEMBL20348686

CC(C)(C)[Si](C)(C)n1c2cc(Br)ccc2c2ccc(Br)cc21

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDGFRA P16234 1/20 0.37
CDK5 Q00535 1/20 0.37
TYRO3 Q06418 1/20 0.37
CHEK1 O14757 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
EGLN1 Q9GZT9 2/20 0.31
MAPT P10636 1/20 0.31
APLNR P35414 2/20 0.31
PDPK1 O15530 1/20 0.31
JAK2 O60674 1/20 0.31
MCL1 Q07820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31550346 1.00 PDGFRA (0.37) PDGFRACDK5TYRO3CHEK1CHRNB2
SCHEMBL18191223 0.85 MAPT (0.41) PDGFRACDK5TYRO3MAPTMCL1
SCHEMBL18191252 0.82 TSPO (0.43) MAPT
SCHEMBL31172482 0.82 TSPO (0.43) MAPT
SCHEMBL28952774 0.78
SCHEMBL22777967 0.74 PDGFRA (0.33) PDGFRACDK5TYRO3APLNR
SCHEMBL29714438 0.74 PDGFRA (0.33) PDGFRACDK5TYRO3APLNR
SCHEMBL6560789 0.73 MCL1 (0.36) MAPTMCL1
SCHEMBL19421853 0.72 PDGFRA (0.38) PDGFRACDK5TYRO3CHEK1EGLN1
SCHEMBL30005815 0.72 GPR3 (0.44) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071014-A1 GROUP III-HALIDE OR LANTHANIDE-HALIDE BIS(PHENYLPHENOXY) METAL-LIGAND COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-12 US disclosed
EP-4565627-A1 GROUP III-HALIDE OR LANTHANIDE-HALIDE BIS(PHENYLPHENOXY) METAL-LIGAND COMPLEXES Dow Global Technologies LLC (US) 2025-06-11 EP disclosed
WO-2024050359-A1 GROUP III-HALIDE OR LANTHANIDE-HALIDE BIS(PHENYLPHENOXY) METAL−LIGAND COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-07 WO disclosed
WO-2024050359-A1 GROUP III-HALIDE OR LANTHANIDE-HALIDE BIS(PHENYLPHENOXY) METAL−LIGAND COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-07 WO disclosed
CN-108350121-B Procatalyst and polymerization process using the same 陶氏环球技术有限责任公司 2021-10-01 CN disclosed
US-11041027-B2 Polymerization process for producing ethylene based polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2021-06-22 US disclosed
CN-107787336-B Polymerization process for preparing ethylene-based polymers 陶氏环球技术有限责任公司 2021-05-28 CN disclosed
CN-107922538-B Polymerization process for the preparation of ethylene-based polymers 陶氏环球技术有限责任公司 2021-05-25 CN disclosed
US-10870713-B2 Procatalyst and polymerization process using the same DOW GLOBAL TECHNOLOGIES LLC (US) 2020-12-22 US disclosed
EP-3736299-A1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS Dow Global Technologies Llc (US) 2020-11-11 EP disclosed
EP-3317313-B1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-02-19 EP disclosed
EP-3317313-B1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-02-19 EP disclosed
US-20180265604-A1 PROCATALYST AND POLYMERIZATION PROCESS USING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-09-20 US disclosed
EP-3356431-A1 PROCATALYST AND POLYMERIZATION PROCESS USING THE SAME Dow Global Technologies LLC (US) 2018-08-08 EP disclosed
US-20180194871-A1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-12 US disclosed
US-20180194871-A1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-12 US disclosed
US-20180186910-A1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-05 US disclosed
US-20180186910-A1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-05 US disclosed
EP-3317313-A1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS Dow Global Technologies Llc (US) 2018-05-09 EP disclosed
WO-2017004462-A1 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071014-A1 GROUP III-HALIDE OR LANTHANIDE-HALIDE BIS(PHENYLPHENOXY) METAL-LIGAND COMPLEXES CCRL2, SCO2, BCL9L PDGFRA 3086/4885CDK5 3325/4885TYRO3 1656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.