Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20340210 | 0.90 | KDM4E (0.58) | KDM4ETSHRALDH1A1KMT2AHPGD | |
| SCHEMBL20340043 | 0.83 | KDM4E (0.64) | KDM4ETSHRALDH1A1KMT2AHPGD | |
| SCHEMBL20339853 | 0.80 | KDM4E (0.60) | KDM4ETSHRALDH1A1KMT2AHPGD | |
| SCHEMBL23183510 | 0.79 | TSHR (0.80) | KDM4ETSHRALDH1A1KMT2AHPGD | |
| SCHEMBL20340192 | 0.79 | KDM4E (0.59) | KDM4ETSHRALDH1A1KMT2AHPGD | |
| SCHEMBL24088076 | 0.79 | LMNA (0.55) | KDM4ETSHRALDH1A1KMT2AHPGD | |
| SCHEMBL24087892 | 0.77 | LMNA (0.53) | KDM4ETSHRALDH1A1KMT2AHPGD | |
| SCHEMBL20350883 | 0.76 | ALDH1A1 (0.47) | KDM4ETSHRALDH1A1KMT2AHPGD | |
| SCHEMBL23849883 | 0.75 | ACMSD (0.48) | KDM4ETSHRALDH1A1KMT2AHPGD | |
| SCHEMBL24088075 | 0.74 | LMNA (0.51) | KDM4ETSHRALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125983-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | MITOBRIDGE, INC. (US) | 2018-07-05 | — | — | WO | disclosed |