SCHEMBL20351960

SCHEMBL20351960

CCN(CC)CCCOc1ncc(C2=CC(NC(=O)c3coc(N)n3)C(Cl)C=C2)s1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PAICS P22234 10/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20338957 0.74 PAICS (0.63) PAICS
SCHEMBL20338924 0.64 PAICS (0.73) PAICS
SCHEMBL20338907 0.56 KDM4E (0.43)
SCHEMBL23011857 0.55 SMYD3 (0.49) PAICS
SCHEMBL21423708 0.54 FBP1 (0.49) PAICS
SCHEMBL479860 0.51 FBP1 (0.65)
SCHEMBL21229110 0.51 ATP4A (0.48)
SCHEMBL9942582 0.50 LMNA (0.36)
SCHEMBL2232095 0.50 LMNA (0.57)
SCHEMBL2628930 0.50 LMNA (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018122550-A1 OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER LIFEARC (GB) 2018-07-05 WO disclosed