SCHEMBL20354513

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5462211	0.91	SLC18A3 (0.58)	GRIN2BHRH3SLC18A3KCNH2CHRNA7
	SCHEMBL3089329	0.91	HRH3 (0.61)	GRIN2BHRH3SLC18A3KCNH2CHRNA7
	SCHEMBL28286738	0.89	SLC18A3 (0.61)	GRIN2BHRH3SLC18A3KCNH2CHRNA7
	SCHEMBL12826402	0.86	SLC18A3 (0.53)	GRIN2BHRH3SLC18A3KCNH2CHRNA7
	SCHEMBL12670642	0.82	GRIN2B (0.65)	GRIN2BHRH3CHRNA7OPRM1OPRK1
	SCHEMBL10263767	0.81	SLC18A3 (0.67)	GRIN2BHRH3SLC18A3KCNH2CHRNA7
	SCHEMBL8569045	0.81	GRIN2B (0.59)	GRIN2BHRH3KCNH2OPRM1OPRD1
	SCHEMBL13468211	0.80	GRIN2B (0.62)	GRIN2BSLC18A3OPRM1OPRK1OPRL1
	SCHEMBL4486847	0.80	CHRNA7 (0.59)	GRIN2BHRH3SLC18A3CHRNA7OPRM1
	SCHEMBL27781945	0.80	SLC18A3 (0.65)	HRH3SLC18A3KCNH2OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.