Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 5/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 5/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 5/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | HAT1 | O14929 | 4/20 | 0.32 |
| ▸ | EP300 | Q09472 | 4/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21569551 | 0.73 | CYP2A6 (0.54) | SLC6A4HTR2A | |
| SCHEMBL21569556 | 0.73 | GPR84 (0.53) | HTR2A | |
| SCHEMBL20354815 | 0.73 | GPR84 (0.53) | SLC6A4HTR2A | |
| SCHEMBL21569552 | 0.73 | HTR2A (0.51) | HTR1DSLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL30729958 | 0.72 | PRKAB2 (0.43) | HTR1DMAT2AAVPR1ADGAT1PRKAB2 | |
| SCHEMBL20354803 | 0.72 | PRKAB2 (0.43) | HTR1DMAT2AAVPR1ADGAT1PRKAB2 | |
| SCHEMBL21569511 | 0.69 | HSD17B10 (0.53) | — | |
| SCHEMBL17915348 | 0.69 | HTR3E (0.45) | AVPR1ADGAT1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL29280797 | 0.67 | HTR2A (0.57) | HTR1DSLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL29280796 | 0.67 | HTR2A (0.57) | HTR1DSLC6A4HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122232-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB PHARMA GMBH (DE) | 2018-07-05 | — | — | WO | disclosed |