SCHEMBL20356705

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20356703	0.86	SMN1; SMN2 (0.48)	MAPTMEN1KMT2ATDP1ALDH1A1
	SCHEMBL20356519	0.83	MAPK8 (0.38)	MAPTALDH1A1HTTSMN1; SMN2NLRP3
	SCHEMBL20356647	0.83	SLC26A6 (0.40)	TDP1ALDH1A1HTTSMN1; SMN2GAA
	Hydrochloric Acid SCHEMBL21526076	0.82	MAPK8 (0.38)	MAPTMEN1KMT2AALDH1A1HTT
	SCHEMBL21526001	0.82	SMN1; SMN2 (0.38)	MAPTTDP1SMN1; SMN2RXFP1GAA
	SCHEMBL20356643	0.81	SLC26A6 (0.41)	TDP1ALDH1A1HTTSMN1; SMN2RXFP1
	SCHEMBL21548876	0.81	SMN1; SMN2 (0.43)	MAPTMEN1KMT2ATDP1ALDH1A1
	Hydrochloric Acid SCHEMBL28322143	0.80	SMN1; SMN2 (0.37)	MAPTTDP1SMN1; SMN2RXFP1GAA
	SCHEMBL21548828	0.79	SMN1; SMN2 (0.36)	MEN1KMT2AALDH1A1CASP3HTT
	SCHEMBL20356659	0.79	SMN1; SMN2 (0.36)	MAPTMEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.