Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.54 |
| ▸ | CPT1A | P50416 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60945 | 0.86 | MEN1 (0.55) | LMNATSHRTUBB4ATUBBTUBA3C | |
| SCHEMBL60282 | 0.84 | CA12 (0.61) | CPT1ACPT1BMEN1ALDH1A1GAA | |
| SCHEMBL23894371 | 0.84 | MEN1 (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL60197 | 0.82 | CASP3 (0.61) | CPT1ACPT1BHSD11B1GRM5 | |
| SCHEMBL59346 | 0.82 | CASP3 (0.64) | CPT1ACPT1BCYP2C9HSD11B1GRM5 | |
| SCHEMBL60252 | 0.81 | CASP3 (0.67) | MAPK1CPT1ACPT1BALDH1A1CYP2C9 | |
| SCHEMBL20116645 | 0.80 | HTT (0.58) | LMNAALOX15TSHRMAPK1TUBB4A | |
| SCHEMBL25171668 | 0.76 | GRM5 (0.67) | GRM5 | |
| SCHEMBL3241112 | 0.76 | TUBB4A (0.69) | LMNAALOX15TSHRMAPK1TUBB4A | |
| SCHEMBL20676418 | 0.76 | LMNA (0.47) | LMNAALOX15TSHRMAPK1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345895-A1 | 1,2,4-OXADIAZOLE BENZOIC ACID COMPOUND AND ITS USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE | PTC Therapeutics, Inc. (US) | 2018-07-11 | — | — | EP | disclosed |