SCHEMBL20360481

SCHEMBL20360481

Fc1cn(-c2ccc(Cl)cc2Br)cn1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
F11 P03951 5/20 0.33
KLKB1 P03952 5/20 0.33
ALDH1A1 P00352 1/20 0.33
S1PR4 O95977 1/20 0.33
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32
OPRK1 P41145 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
IDO1 P14902 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30702180 1.00 F11 (0.33) F11KLKB1ALDH1A1S1PR4OPRM1
SCHEMBL20359777 0.83 ALDH1A1 (0.35) F11KLKB1ALDH1A1OPRM1OPRD1
SCHEMBL30702162 0.83 ALDH1A1 (0.35) F11KLKB1ALDH1A1OPRM1OPRD1
SCHEMBL30702204 0.80 SCN9A (0.38) F11KLKB1ALDH1A1L3MBTL1
SCHEMBL20360626 0.80 F11 (0.36) F11KLKB1ALDH1A1OPRM1OPRD1
SCHEMBL20359068 0.80 SCN9A (0.38) F11KLKB1ALDH1A1L3MBTL1
SCHEMBL30702168 0.80 F11 (0.36) F11KLKB1ALDH1A1OPRM1OPRD1
SCHEMBL20359185 0.77 TSHR (0.35) ALDH1A1S1PR4OPRM1OPRD1OPRK1
SCHEMBL30702135 0.77 TSHR (0.35) ALDH1A1S1PR4OPRM1OPRD1OPRK1
SCHEMBL18376082 0.75 MAP4K4 (0.41) F11KLKB1ALDH1A1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282748-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2025-09-11 US disclosed
CN-113292539-B Substituted oxopyridine derivatives 拜耳制药股份公司 2023-12-22 CN disclosed
US-20230024752-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2023-01-26 US disclosed
US-20230024752-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2023-01-26 US disclosed
US-11180471-B2 Substituted oxopyridine derivatives BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2021-11-23 US disclosed
US-11180471-B2 Substituted oxopyridine derivatives BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2021-11-23 US disclosed
CN-113292539-A Substituted oxopyridine derivatives 拜耳制药股份公司 2021-08-24 CN disclosed
CN-108026072-B Substituted oxopyridine derivatives 拜耳制药股份公司 2021-08-17 CN disclosed
EP-3319956-B1 SUBSTITUTED OXOPYRIDINE DERIVATIVES Bayer Pharma AG (DE) 2021-01-06 EP disclosed
EP-3319956-B1 SUBSTITUTED OXOPYRIDINE DERIVATIVES Bayer Pharma AG (DE) 2021-01-06 EP disclosed
US-10421742-B2 Substituted oxopyridine derivatives BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2019-09-24 US disclosed
US-10421742-B2 Substituted oxopyridine derivatives BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2019-09-24 US disclosed
US-20180194745-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-07-12 US disclosed
US-20180194745-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-07-12 US disclosed
US-20180194745-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10421742-B2 Substituted oxopyridine derivatives OGFOD1, VASP, PNPO F11 928/4885KLKB1 2656/4885ALDH1A1 2345/4885
US-11180471-B2 Substituted oxopyridine derivatives OGFOD1, VASP, PNPO F11 928/4885KLKB1 2656/4885ALDH1A1 2345/4885
US-20180194745-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES OGFOD1, VASP, PNPO F11 928/4885KLKB1 2656/4885ALDH1A1 2345/4885
US-20250282748-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES OGFOD1, VASP, PNPO F11 928/4885KLKB1 2656/4885ALDH1A1 2345/4885
US-20230024752-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES OGFOD1, VASP, PNPO F11 928/4885KLKB1 2656/4885ALDH1A1 2345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.