Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20359185 | 1.00 | TSHR (0.35) | TSHRHTTOPRM1OPRD1OPRK1 | |
| SCHEMBL20344947 | 0.82 | MAPK14 (0.36) | OPRM1S1PR4PSEN1PSEN2APH1B | |
| SCHEMBL16054891 | 0.82 | IDH1 (0.36) | S1PR4PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20359777 | 0.80 | ALDH1A1 (0.35) | TSHRHTTOPRM1OPRD1OPRK1 | |
| SCHEMBL30702162 | 0.80 | ALDH1A1 (0.35) | TSHRHTTOPRM1OPRD1OPRK1 | |
| SCHEMBL30702180 | 0.77 | F11 (0.33) | TSHRHTTOPRM1OPRD1OPRK1 | |
| SCHEMBL20360481 | 0.77 | F11 (0.33) | TSHRHTTOPRM1OPRD1OPRK1 | |
| SCHEMBL30702147 | 0.75 | P2RX7 (0.45) | TSHRHTTOPRM1OPRD1OPRK1 | |
| SCHEMBL18797501 | 0.75 | P2RX7 (0.45) | TSHRHTTOPRM1OPRD1OPRK1 | |
| SCHEMBL16043335 | 0.74 | MAP4K4 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292539-B | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2023-12-22 | — | — | CN | disclosed |