SCHEMBL20360667

SCHEMBL20360667

CC1(C)OB(c2c3ccccc3c(-c3ccncc3)c3ccccc23)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPL P06858 6/20 0.40
LIPG Q9Y5X9 6/20 0.40
IMPDH2 P12268 2/20 0.40
NOTUM Q6P988 1/20 0.34
MAPK14 Q16539 6/20 0.33
TGFBR1 P36897 1/20 0.33
HTT P42858 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
ATAD2 Q6PL18 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1006183 0.87 LIPG (0.53) LPLLIPGMAPK1MAPT
SCHEMBL29362504 0.87 LIPG (0.53) LPLLIPGMAPK1MAPT
SCHEMBL29581600 0.85 PDE10A (0.34) LPLLIPGIMPDH2TGFBR1MAPK1
SCHEMBL18788571 0.85 PDE10A (0.34) LPLLIPGIMPDH2TGFBR1MAPK1
SCHEMBL16473593 0.84 LIPG (0.59) LPLLIPGMAPT
SCHEMBL19713462 0.84 LPL (0.44) LPLLIPGHTTHSD17B10RAB9A
SCHEMBL23957176 0.83 LPL (0.46) LPLLIPGMAPK1
SCHEMBL13855171 0.83 LPL (0.46) LPLLIPGMAPK1
SCHEMBL22139774 0.83 LIPG (0.62) LPLLIPG
SCHEMBL1505886 0.83 LPL (0.45) LPLLIPGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10854823-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-12-01 US disclosed
US-20180198074-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10854823-B2 Heterocyclic compound and organic light-emitting device including the same CRY1, CRY2, CYP1A1 LPL 2980/4885LIPG 3765/4885IMPDH2 1381/4885
US-20180198074-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CYP1A1 LPL 2980/4885LIPG 3765/4885IMPDH2 1381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.