SCHEMBL203615

SCHEMBL203615

O=C(OCC1CC2C=CC1C2)c1cccc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 2/20 0.44
HRH3 Q9Y5N1 2/20 0.43
ALDH1A1 P00352 6/20 0.42
KDM4E B2RXH2 6/20 0.42
CDC25A P30304 1/20 0.41
CDC25C P30307 1/20 0.41
ADRB2 P07550 2/20 0.41
ADRB1 P08588 2/20 0.41
ADRB3 P13945 2/20 0.41
DRD3 P35462 1/20 0.41
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
NPC1 O15118 1/20 0.40
HPGD P15428 3/20 0.40
MAPT P10636 1/20 0.40
CACNA1B Q00975 2/20 0.39
APBA1 Q02410 2/20 0.39
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200409 0.88 HRH3 (0.46) CDC25BHRH3ALDH1A1KDM4ECDC25A
SCHEMBL200050 0.82 KDM4E (0.42) ALDH1A1KDM4EPOLBKMT2AHPGD
SCHEMBL201988 0.80 CHRNB2 (0.56) ALDH1A1KDM4ETDP1
SCHEMBL5071739 0.79 CYP3A4 (0.58) ALDH1A1KDM4EPOLBGAAKMT2A
SCHEMBL4403504 0.79 PPM1B (0.47) ALDH1A1KDM4EKMT2ANPC1TDP1
SCHEMBL14435505 0.79 PPM1B (0.47) ALDH1A1KDM4EKMT2ANPC1TDP1
SCHEMBL13498624 0.78 CDC25B (0.52) CDC25BHRH3ALDH1A1KDM4ECDC25A
SCHEMBL2114876 0.78 CDC25B (0.52) CDC25BHRH3ALDH1A1KDM4ECDC25A
SCHEMBL2899404 0.78 BCHE (0.46) CDC25BHRH3ALDH1A1KDM4EPOLB
SCHEMBL200309 0.78 ALDH1A1 (0.46) HRH3ALDH1A1KDM4EADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
WO-2006098162-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2006-09-21 WO disclosed
WO-2006082818-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-08-10 WO disclosed
US-7008569-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-03-07 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed
EP-1395855-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-10 EP disclosed
WO-2002088784-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed