Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | QDPR | P09417 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20364013 | 0.78 | MAPT (0.48) | SMN1; SMN2KDM4EHTTPABPC1APOBEC3A | |
| SCHEMBL5159873 | 0.78 | KDM4E (0.50) | SMN1; SMN2KDM4EHTTCYP3A4 | |
| SCHEMBL18748287 | 0.75 | MAPT (0.73) | SMN1; SMN2PABPC1APOBEC3AEIF4HAPOBEC3G | |
| SCHEMBL13907332 | 0.75 | MAPT (0.73) | SMN1; SMN2PABPC1APOBEC3AEIF4HAPOBEC3G | |
| SCHEMBL13907285 | 0.75 | MAPT (0.73) | SMN1; SMN2PABPC1APOBEC3AEIF4HAPOBEC3G | |
| SCHEMBL19270240 | 0.75 | MAPT (0.73) | SMN1; SMN2PABPC1APOBEC3AEIF4HAPOBEC3G | |
| SCHEMBL8105523 | 0.75 | PABPC1 (0.55) | SMN1; SMN2KDM4EHTTPABPC1APOBEC3A | |
| SCHEMBL27430947 | 0.75 | MAPT (0.55) | SMN1; SMN2KDM4EPABPC1APOBEC3AEIF4H | |
| Hydrochloric Acid SCHEMBL3825788 | 0.74 | PABPC1 (0.53) | SMN1; SMN2KDM4EHTTPABPC1APOBEC3A | |
| SCHEMBL13915993 | 0.72 | MAPT (0.79) | SMN1; SMN2KDM4EPABPC1APOBEC3AEIF4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194995-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (FR) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194995-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | EYA2, EYA3, ALDH1A2 | SMN1; SMN2 4631/4885KDM4E 1575/4885HTT 1109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.