Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12623931 | 0.92 | HCRTR1 (0.48) | HCRTR1HCRTR2L3MBTL1ALDH1A1NAMPT | |
| SCHEMBL15426422 | 0.89 | HCRTR1 (0.51) | HCRTR1HCRTR2L3MBTL1ALDH1A1GPR119 | |
| SCHEMBL12627185 | 0.88 | HCRTR1 (0.50) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL12655883 | 0.88 | HCRTR1 (0.50) | HCRTR1HCRTR2L3MBTL1ALDH1A1NAMPT | |
| SCHEMBL12656193 | 0.87 | L3MBTL1 (0.57) | HCRTR1HCRTR2L3MBTL1ALDH1A1GPR119 | |
| SCHEMBL15426424 | 0.86 | HCRTR1 (0.48) | HCRTR1HCRTR2L3MBTL1ALDH1A1F13A1 | |
| SCHEMBL21202626 | 0.80 | HCRTR1 (0.49) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL12626973 | 0.80 | USP2 (0.46) | HCRTR1HCRTR2NAMPTGPR119 | |
| SCHEMBL22368466 | 0.80 | L3MBTL1 (0.52) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL20365037 | 0.80 | HCRTR1 (0.50) | HCRTR1HCRTR2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160251374-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | BURNS BARBIER LINDSAY (US) | 2016-09-01 | — | — | US | disclosed |
| US-9340558-B2 | Filamin a binding anti-inflammatory and analgesic | PAIN THERAPEUTICS INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-8653068-B2 | Filamin A binding anti-inflammatory and analgesic | PAIN THERAPEUTICS, INC. (US) | 2014-02-18 | — | — | US | disclosed |
| US-20110105487-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | PAIN THERAPEUTICS | 2011-05-05 | — | — | US | disclosed |
| US-20110105481-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | PAIN THERAPEUTICS | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160251374-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | FLNA, FLNB, OPRK1 | HCRTR1 3880/4885HCRTR2 3876/4885L3MBTL1 3291/4885 |
| US-20110105487-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | FLNA, FLNB, FPR1 | HCRTR1 4172/4885HCRTR2 4089/4885L3MBTL1 4055/4885 |
| US-20110105481-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | FLNA, FLNB, OPRK1 | HCRTR1 3880/4885HCRTR2 3876/4885L3MBTL1 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.