SCHEMBL20370282

SCHEMBL20370282

c1c[nH]c(-c2ccc(-c3ccc[nH]3)c3nc4c5ccccc5c5ccccc5c4nc23)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 2/20 0.39
MAPK9 P45984 2/20 0.39
MAPK10 P53779 2/20 0.39
MAPT P10636 3/20 0.38
MEN1 O00255 2/20 0.38
POLB P06746 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 2/20 0.38
PKM P14618 1/20 0.38
BLM P54132 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CDK2 P24941 1/20 0.35
ALDH1A1 P00352 2/20 0.33
ADORA2A P29274 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CDK5 Q00535 1/20 0.33
CDK5R1 Q15078 1/20 0.33
ABCB1 P08183 3/20 0.33
ABCG2 Q9UNQ0 3/20 0.33
ADRA1D P25100 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15499537 0.86 CDK5 (0.38) MEN1KMT2ACDK2ADORA2ACDK5
SCHEMBL15499640 0.75 AURKA (0.37) MAPK8MAPK9MAPK10MAPTKMT2A
SCHEMBL668870 0.72 ALDH1A1 (0.50) MAPTMEN1POLBKMT2ALMNA
SCHEMBL2289477 0.71 KDM4E (0.50) TDP1ALDH1A1CDK5CDK5R1AURKA
SCHEMBL20370289 0.71 AURKA (0.39) MAPTCDK2CDK5CDK5R1ADRA1D
SCHEMBL12561729 0.70 PTGES (0.54) MAPTMEN1POLBKMT2ALMNA
SCHEMBL15416821 0.70 KDR (0.47) MAPK8MAPK9CDK2ADORA2ACDK5
SCHEMBL20370283 0.70 MAPT (0.44) MAPK8MAPTMEN1POLBKMT2A
SCHEMBL15499589 0.70 ADORA2A (0.32) ADORA2ACDK5CDK5R1
SCHEMBL30471900 0.70 MAPT (0.48) MAPTMEN1POLBKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180198128-A1 FLUORINATED-POLYMER COATED ELECTRODES SOUTH DAKOTA BOARD OF REGENTS (US) 2018-07-12 US disclosed
US-20180198128-A1 FLUORINATED-POLYMER COATED ELECTRODES SOUTH DAKOTA BOARD OF REGENTS (US) 2018-07-12 US disclosed