Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 5/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15499537 | 0.87 | CDK5 (0.38) | AURKAKDRCDK5CDK5R1KMT2A | |
| SCHEMBL20370282 | 0.75 | MAPK8 (0.39) | AURKAKDRNPC1CDK5CDK5R1 | |
| SCHEMBL15499641 | 0.72 | PIM1 (0.32) | ACHEPIM1PIM2PIM3 | |
| SCHEMBL9864565 | 0.70 | LMNA (0.52) | AURKAKDRNPC1CDK5CDK5R1 | |
| SCHEMBL20370289 | 0.68 | AURKA (0.39) | AURKAKDRCDK5CDK5R1MAPT | |
| SCHEMBL15416821 | 0.68 | KDR (0.47) | AURKAKDRNPC1GBA1CDK5 | |
| SCHEMBL15499589 | 0.67 | ADORA2A (0.32) | CDK5CDK5R1 | |
| SCHEMBL13554698 | 0.67 | KDM4E (0.48) | NPC1PIM1PIM2RAB9AALDH1A1 | |
| SCHEMBL20019709 | 0.66 | PARP1 (0.44) | AURKAKDRCDK5CDK5R1RAB9A | |
| SCHEMBL12930294 | 0.66 | AURKA (0.37) | AURKAKDRALDH1A1MAPTADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392395-B2 | Nitrogen-containing aromatic compounds and metal complexes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-08-27 | — | — | US | disclosed |
| US-20140066290-A1 | CATHODE CATALYST FOR AIR SECONDARY BATTERY AND AIR SECONDARY BATTERY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392395-B2 | Nitrogen-containing aromatic compounds and metal complexes | TYR, MT-CO2, SOD1 | AURKA 576/4885KDR 1923/4885NPC1 4030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.