Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.30 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15499640 | 0.87 | AURKA (0.37) | CDK5CDK5R1AURKAKDRCDK2 | |
| SCHEMBL20370282 | 0.86 | MAPK8 (0.39) | CDK5CDK5R1AURKAKDRCDK2 | |
| SCHEMBL20370289 | 0.78 | AURKA (0.39) | CDK5CDK5R1AURKAKDRCDK2 | |
| SCHEMBL15499589 | 0.77 | ADORA2A (0.32) | CDK5CDK5R1ADORA2A | |
| SCHEMBL9864565 | 0.72 | LMNA (0.52) | CDK5CDK5R1AURKAKDRADRA1A | |
| SCHEMBL15416821 | 0.72 | KDR (0.47) | CDK5AURKAKDRCDK2ADORA2A | |
| SCHEMBL31408898 | 0.72 | AURKA (0.42) | AURKAKDRCDK2ADORA2AADRA1D | |
| SCHEMBL20370293 | 0.71 | AURKA (0.39) | CDK5CDK5R1AURKAKDRCDK2 | |
| SCHEMBL20019709 | 0.71 | PARP1 (0.44) | CDK5CDK5R1AURKAKDRADORA2A | |
| SCHEMBL17708582 | 0.71 | BRAF (0.39) | CDK5CDK5R1AURKAKDRCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392395-B2 | Nitrogen-containing aromatic compounds and metal complexes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-08-27 | — | — | US | disclosed |
| EP-2493890-B1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND METAL COMPLEXES | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |
| US-20140066290-A1 | CATHODE CATALYST FOR AIR SECONDARY BATTERY AND AIR SECONDARY BATTERY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392395-B2 | Nitrogen-containing aromatic compounds and metal complexes | TYR, MT-CO2, SOD1 | CDK5 2533/4885CDK5R1 3316/4885AURKA 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.