Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18804533 | 0.72 | ALDH1A1 (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL23147927 | 0.71 | KCNH2 (0.31) | — | |
| SCHEMBL20374808 | 0.69 | ADORA2A (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL18101009 | 0.67 | MEN1 (0.37) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL20370771 | 0.66 | GRIN2B (0.36) | — | |
| SCHEMBL19879922 | 0.63 | AOC3 (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL16650458 | 0.63 | KDM5A (0.43) | ALDH1A1LMNAHPGD | |
| SCHEMBL15520820 | 0.62 | PDE4A (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL10322016 | 0.61 | SCD (0.37) | MEN1KMT2A | |
| SCHEMBL15043729 | 0.61 | BMPR1B (0.41) | MEN1KMT2AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194755-A1 | Tetrahydropyranyl Benzamide Derivatives | ELI LILLY AND COMPANY | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194755-A1 | Tetrahydropyranyl Benzamide Derivatives | INSR, GPR119, GLP1R | MEN1 934/4885KMT2A 2822/4885ALDH1A1 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.