Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038199 | 0.83 | KDM4E (0.46) | ANO1KMT2AMEN1EGFRKDM4E | |
| SCHEMBL2044582 | 0.83 | MAPT (0.57) | KMT2AMEN1EGFRKDM4ENPSR1 | |
| SCHEMBL2042919 | 0.81 | MEN1 (0.41) | KMT2AMEN1EGFRKDM4ENPSR1 | |
| SCHEMBL2038957 | 0.80 | MEN1 (0.42) | KMT2AMEN1EGFRKDM4ENPSR1 | |
| SCHEMBL13506789 | 0.76 | PDE2A (0.40) | KMT2AMEN1KDM4ENPSR1NPC1 | |
| SCHEMBL2046992 | 0.74 | NPSR1 (0.50) | KMT2AMEN1KDM4ENPSR1NPC1 | |
| SCHEMBL2043902 | 0.72 | NPSR1 (0.45) | KMT2AMEN1KDM4ENPSR1LMNA | |
| SCHEMBL2044884 | 0.72 | GAA (0.40) | KMT2AMEN1KDM4ENPSR1NPC1 | |
| SCHEMBL2038649 | 0.72 | MAP2K4 (0.41) | KMT2AMEN1KDM4EGAAMAPT | |
| SCHEMBL20376006 | 0.71 | MAOB (0.56) | KMT2AMEN1EGFRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516400-B1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RES & DEV (FR) | 2017-03-22 | — | — | EP | claimed |
| US-20130178633-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-07-11 | — | — | US | claimed |
| EP-2516400-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | Galderma Research & Development (FR) | 2012-10-31 | — | — | EP | claimed |
| US-10202346-B2 | Phenol derivatives and the pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2019-02-12 | — | — | US | disclosed |
| EP-2516400-B1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RES & DEV (FR) | 2017-03-22 | — | — | EP | disclosed |
| US-20160068488-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | COLLETTE PATRICE LUCIEN MAURICE (FR) | 2016-03-10 | — | — | US | disclosed |
| US-20130178633-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-07-11 | — | — | US | disclosed |
| EP-2516400-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | Galderma Research & Development (FR) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011077046-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068488-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | TYR, MITF, CUTA | ANO1 3360/4885KMT2A 2277/4885MEN1 3059/4885 |
| US-20130178633-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | TYR, MITF, CUTA | ANO1 3360/4885KMT2A 2277/4885MEN1 3059/4885 |
| US-10202346-B2 | Phenol derivatives and the pharmaceutical or cosmetic use thereof | TYR, MITF, CUTA | ANO1 3360/4885KMT2A 2277/4885MEN1 3059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.