Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037130 | 0.83 | ANO1 (0.46) | KDM4EKMT2AMEN1ANO1ALDH1A1 | |
| SCHEMBL2038341 | 0.81 | MAPT (0.54) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2039704 | 0.78 | KMT2A (0.43) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2042919 | 0.76 | MEN1 (0.41) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2048102 | 0.75 | KMT2A (0.50) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL20376006 | 0.74 | MAOB (0.56) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2042255 | 0.72 | NPSR1 (0.50) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL27770274 | 0.70 | EGFR (0.74) | ALDH1A1MAPTTDP1EGFRSYK | |
| SCHEMBL27770271 | 0.69 | EGFR (0.60) | ALDH1A1MAPTTDP1APPEGFR | |
| SCHEMBL25442715 | 0.69 | EGFR (0.51) | KDM4EKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202346-B2 | Phenol derivatives and the pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2019-02-12 | — | — | US | claimed |
| EP-2516400-B1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RES & DEV (FR) | 2017-03-22 | — | — | EP | claimed |
| US-20130178633-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-07-11 | — | — | US | claimed |
| US-10202346-B2 | Phenol derivatives and the pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2019-02-12 | — | — | US | disclosed |
| EP-2516400-B1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RES & DEV (FR) | 2017-03-22 | — | — | EP | disclosed |
| US-20160068488-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | COLLETTE PATRICE LUCIEN MAURICE (FR) | 2016-03-10 | — | — | US | disclosed |
| US-20130178633-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-07-11 | — | — | US | disclosed |
| EP-2516400-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | Galderma Research & Development (FR) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011077046-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068488-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | TYR, MITF, CUTA | KDM4E 1507/4885KMT2A 2277/4885MEN1 3059/4885 |
| US-20130178633-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | TYR, MITF, CUTA | KDM4E 1507/4885KMT2A 2277/4885MEN1 3059/4885 |
| US-10202346-B2 | Phenol derivatives and the pharmaceutical or cosmetic use thereof | TYR, MITF, CUTA | KDM4E 1507/4885KMT2A 2277/4885MEN1 3059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.