Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17699257 | 0.88 | PTGDR (0.42) | NPSR1HSD17B10NPC1CYP2C19MEN1 | |
| SCHEMBL17699259 | 0.85 | MTNR1A (0.42) | NPSR1GAALMNAL3MBTL1CYP2C19 | |
| SCHEMBL2042255 | 0.83 | NPSR1 (0.50) | NPSR1HSD17B10NPC1LMNARAB9A | |
| SCHEMBL2044884 | 0.82 | GAA (0.40) | NPSR1HSD17B10NPC1GAALMNA | |
| SCHEMBL2043902 | 0.82 | NPSR1 (0.45) | NPSR1GAALMNAL3MBTL1PKM | |
| SCHEMBL2040677 | 0.82 | NPSR1 (0.67) | NPSR1HSD17B10NPC1GAAL3MBTL1 | |
| SCHEMBL2047920 | 0.80 | NPSR1 (0.56) | NPSR1HSD17B10NPC1LMNAL3MBTL1 | |
| SCHEMBL2042920 | 0.78 | GAA (0.40) | NPSR1NPC1GAALMNAL3MBTL1 | |
| SCHEMBL2042919 | 0.76 | MEN1 (0.41) | NPSR1HSD17B10GAALMNAL3MBTL1 | |
| SCHEMBL2040233 | 0.76 | NPSR1 (0.50) | NPSR1HSD17B10NPC1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516398-B1 | PHENOLIC DERIVATIVES, AND THEIR PHARMACEUTICAL OR COSMETIC USE | GALDERMA RES & DEV (FR) | 2018-03-21 | — | — | EP | claimed |
| US-9505720-B2 | Phenol derivatives and pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-11-29 | — | — | US | claimed |
| US-20160115132-A1 | NOVEL PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-04-28 | — | — | US | claimed |
| US-9050266-B2 | Phenol derivatives and pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-06-09 | — | — | US | claimed |
| US-20140275536-A1 | NOVEL PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-09-18 | — | — | US | claimed |
| EP-2516398-A2 | NOVEL PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | Galderma Research & Development (FR) | 2012-10-31 | — | — | EP | claimed |
| WO-2011077043-A2 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-06-30 | — | — | WO | claimed |
| EP-2516398-B1 | PHENOLIC DERIVATIVES, AND THEIR PHARMACEUTICAL OR COSMETIC USE | GALDERMA RES & DEV (FR) | 2018-03-21 | — | — | EP | disclosed |
| US-20170037015-A1 | NOVEL PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2017-02-09 | — | — | US | disclosed |
| US-9505720-B2 | Phenol derivatives and pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-11-29 | — | — | US | disclosed |
| US-20160115132-A1 | NOVEL PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-04-28 | — | — | US | disclosed |
| US-9050266-B2 | Phenol derivatives and pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-06-09 | — | — | US | disclosed |
| US-20140275536-A1 | NOVEL PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2014-09-18 | — | — | US | disclosed |
| EP-2516398-A2 | NOVEL PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | Galderma Research & Development (FR) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011077043-A2 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037015-A1 | NOVEL PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | TYR, MITF, TEAD3 | NPSR1 1708/4885HSD17B10 145/4885NPC1 799/4885 |
| US-20140275536-A1 | NOVEL PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | TYR, MITF, CUTA | NPSR1 2580/4885HSD17B10 204/4885NPC1 1091/4885 |
| US-20160115132-A1 | NOVEL PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | TYR, MITF, TEAD3 | NPSR1 1708/4885HSD17B10 145/4885NPC1 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.