Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.43 |
| ▸ | NPC1 | O15118 | 11/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037498 | 0.83 | RAB9A (0.43) | RAB9ANPC1PKMKMT2AMAPT | |
| SCHEMBL2037579 | 0.80 | RAB9A (0.42) | RAB9ANPC1PKMKMT2AMAPT | |
| SCHEMBL29682609 | 0.78 | NPC1 (0.55) | RAB9ANPC1PKMMAPTCHRNB2 | |
| SCHEMBL2037831 | 0.77 | CHRNB2 (0.64) | RAB9ANPC1PKMMAPTCHRNB2 | |
| SCHEMBL2037773 | 0.76 | NPC1 (0.38) | RAB9ANPC1PKMKMT2AMAPT | |
| SCHEMBL2036752 | 0.75 | NPC1 (0.46) | RAB9ANPC1PKMKMT2AMAPT | |
| SCHEMBL2040507 | 0.74 | NPC1 (0.73) | RAB9ANPC1MAPTCHRNB2CHRNA5 | |
| SCHEMBL2034759 | 0.74 | NPC1 (0.51) | RAB9ANPC1PKMKMT2AMAPT | |
| SCHEMBL2039666 | 0.72 | NPC1 (0.46) | RAB9ANPC1KMT2AMAPTCHRNB2 | |
| SCHEMBL2033604 | 0.71 | CHRNB2 (0.72) | RAB9ANPC1MAPTCHRNB2CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073298-A1 | TETRAZOLE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2011-06-23 | — | — | WO | claimed |
| WO-2011073298-A1 | TETRAZOLE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2011-06-23 | — | — | WO | disclosed |