Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.43 |
| ▸ | NPC1 | O15118 | 13/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037353 | 0.83 | RAB9A (0.43) | RAB9ANPC1PKMRECQLMAPT | |
| SCHEMBL2037831 | 0.80 | CHRNB2 (0.64) | RAB9ANPC1PKMMAPTCHRNB2 | |
| SCHEMBL2040546 | 0.80 | RAB9A (0.43) | RAB9ANPC1PKMRECQLMAPT | |
| SCHEMBL2039061 | 0.75 | CHRNB2 (0.74) | RAB9ANPC1MAPTCHRNB2CHRNA5 | |
| SCHEMBL2036415 | 0.72 | CHRNB2 (0.74) | RAB9ANPC1PKMMAPTCHRNB2 | |
| SCHEMBL13745367 | 0.71 | DYRK1A (0.46) | RAB9ANPC1PKMMAPT | |
| SCHEMBL2037773 | 0.70 | NPC1 (0.38) | RAB9ANPC1PKMMAPTCHRNB2 | |
| SCHEMBL17145305 | 0.66 | SMN1; SMN2 (0.46) | KMT2AL3MBTL1MEN1 | |
| SCHEMBL4853177 | 0.64 | PTGS1 (0.38) | MAPT | |
| SCHEMBL4699663 | 0.64 | GRM5 (0.63) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073298-A1 | TETRAZOLE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2011-06-23 | — | — | WO | claimed |
| WO-2011073298-A1 | TETRAZOLE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2011-06-23 | — | — | WO | disclosed |