Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.42 |
| ▸ | NPC1 | O15118 | 13/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040546 | 0.84 | RAB9A (0.43) | RAB9ANPC1PKMKMT2AMAPT | |
| SCHEMBL2037353 | 0.80 | RAB9A (0.43) | RAB9ANPC1PKMKMT2AMAPT | |
| SCHEMBL2036940 | 0.78 | CHRNB2 (0.62) | RAB9ANPC1PKMMAPTCHRNB2 | |
| SCHEMBL2036408 | 0.77 | NPC1 (0.41) | RAB9ANPC1PKMKMT2ACHRNB2 | |
| SCHEMBL2041201 | 0.73 | RAB9A (0.59) | RAB9ANPC1PKMMAPTKDM4E | |
| SCHEMBL2040507 | 0.73 | NPC1 (0.73) | RAB9ANPC1MAPTKDM4ECHRNB2 | |
| SCHEMBL2034759 | 0.70 | NPC1 (0.51) | RAB9ANPC1PKMKMT2AMAPT | |
| SCHEMBL2036752 | 0.68 | NPC1 (0.46) | RAB9ANPC1PKMKMT2AMAPT | |
| SCHEMBL2039666 | 0.68 | NPC1 (0.46) | RAB9ANPC1KMT2AMAPTKDM4E | |
| SCHEMBL2033604 | 0.68 | CHRNB2 (0.72) | RAB9ANPC1MAPTCHRNB2CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073298-A1 | TETRAZOLE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2011-06-23 | — | — | WO | claimed |
| WO-2011073298-A1 | TETRAZOLE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2011-06-23 | — | — | WO | disclosed |