Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FABP7 | O15540 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11908671 | 1.00 | LMNA (0.46) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL28630522 | 1.00 | LMNA (0.46) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL947840 | 1.00 | LMNA (0.46) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL3365931 | 0.98 | LMNA (0.47) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL11908078 | 0.84 | ALDH1A1 (0.48) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL11908819 | 0.84 | ALDH1A1 (0.48) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL2135609 | 0.84 | KDM4E (0.44) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL13888469 | 0.84 | KDM4E (0.44) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL11909877 | 0.82 | ALDH1A1 (0.49) | LMNAKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL2137300 | 0.82 | LMNA (0.40) | LMNAKDM4EALDH1A1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10675359-B2 | Enzymatic conjugation of antibodies | INNATE PHARMA (FR) | 2020-06-09 | — | — | US | disclosed |
| EP-3240573-B1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | INNATE PHARMA (FR) | 2019-03-20 | — | — | EP | disclosed |
| US-20180193476-A1 | ENZYMATIC CONJUGATION OF ANTIBODIES | ARARIS BIOTECH LTD (CH) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10675359-B2 | Enzymatic conjugation of antibodies | DNPEP, MPO, FCGR3B | LMNA 4260/4885KDM4E 3043/4885ALDH1A1 161/4885 |
| US-20180193476-A1 | ENZYMATIC CONJUGATION OF ANTIBODIES | DNPEP, MPO, FCGR3B | LMNA 4260/4885KDM4E 3043/4885ALDH1A1 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.