SCHEMBL20376286

SCHEMBL20376286

C/C=C1/CC(C(C)CCCCCS(=O)(=O)Cl)C(=O)c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC25A5 P05141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20376256 0.86 S100A4 (0.39) SLC25A5
SCHEMBL20201727 0.86 S100A4 (0.39) SLC25A5
SCHEMBL20208493 0.86 S100A4 (0.39) SLC25A5
SCHEMBL20201784 0.69 S100A4 (0.40) SLC25A5
SCHEMBL20376450 0.69 S100A4 (0.40) SLC25A5
SCHEMBL17593177 0.64 S100A4 (0.43)
SCHEMBL20201781 0.64 HDAC4 (0.42) SLC25A5
SCHEMBL20201723 0.64 HDAC4 (0.42) SLC25A5
SCHEMBL17614764 0.63 METAP1 (0.41) SLC25A5
SCHEMBL12237101 0.60 ACHE (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018128720-A1 URACIL CONTAINING COMPOUNDS CV6 THERAPEUTICS (NI) LIMITED (GB) 2018-07-12 WO disclosed