Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 11/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950444 | 0.70 | HTR3E (0.53) | — | |
| SCHEMBL5606524 | 0.69 | CES2 (0.50) | — | |
| SCHEMBL17287802 | 0.69 | CSNK1D (0.68) | CSNK1DDYRK1AACP1CSNK2A2CSNK2B | |
| SCHEMBL28488116 | 0.69 | SMN1; SMN2 (0.54) | — | |
| SCHEMBL27551140 | 0.68 | FBP1 (0.41) | CSNK2A2CSNK2BCSNK2A1CSNK2A3LIPE | |
| Hydrochloric Acid SCHEMBL28640787 | 0.68 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL6542786 | 0.67 | SMN1; SMN2 (0.43) | DYRK1A | |
| SCHEMBL17287559 | 0.67 | CSNK1D (1.00) | CSNK1DDYRK1AACP1 | |
| SCHEMBL7617152 | 0.67 | P2RX1 (0.39) | — | |
| SCHEMBL27742325 | 0.67 | TMPRSS4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3348550-A1 | SUBSTITUTED BENZOTHIAZOLES AND THERAPEUTIC USES THEREOF FOR THE TREATMENT OF HUMAN DISEASES | Consejo Superior de Investigaciones Cientificas (CSIC) (ES) | 2018-07-18 | — | — | EP | disclosed |