Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742325 | 0.88 | TMPRSS4 (0.47) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL27742328 | 0.85 | P2RX1 (0.44) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL7612259 | 0.82 | LMNA (0.44) | LMNAHPGDMEN1KMT2A | |
| SCHEMBL5606524 | 0.81 | CES2 (0.50) | LMNATP53CETPMEN1KMT2A | |
| SCHEMBL7617455 | 0.80 | MPO (0.41) | MPONTRK1CDK19MEN1GRIK1 | |
| SCHEMBL28217598 | 0.77 | PTGIR (0.46) | LMNAMEN1KMT2ACES2 | |
| SCHEMBL27721413 | 0.76 | P2RX1 (0.43) | P2RX1LMNAMEN1KMT2ACES2 | |
| SCHEMBL7740235 | 0.76 | FLT1 (0.51) | PPARG | |
| SCHEMBL3674538 | 0.75 | CES2 (0.40) | P2RX1SLC2A1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL7741946 | 0.74 | KDM4E (0.49) | MPOHPGDMEN1GRIK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906273-B1 | PHENYL DERIVATIVES CONTAINING AN ACIDIC GROUP, THEIR PREPARATION AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH AS (DK) | 2002-10-16 | — | — | EP | disclosed |
| US-6417393-B1 | TREATMENT OF SICKLE-CELL ANEMIA, BRAIN EDEMA FROM TUMORS OR ISCHEMIA, DIARRHEA, AND GLAUCOMA; HYPOTENSIVE, WOUND HEALING, ANTIINFLAMMATORY AND ANTIALLERGEN AGENTS | NEUROSEARCH A/S (DK) | 2002-07-09 | — | — | US | disclosed |
| EP-0906273-A1 | PHENYL DERIVATIVES CONTAINING AN ACIDIC GROUP, THEIR PREPARATION AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997045400-A1 | PHENYL DERIVATIVES CONTAINING AN ACIDIC GROUP, THEIR PREPARATION AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1997-12-04 | — | — | WO | disclosed |