Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SDHB | P21912 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20393622 | 0.86 | PTGS2 (0.44) | PTGS2KCNH2HPGDLMNAHTT | |
| SCHEMBL20393763 | 0.85 | PTGS2 (0.34) | PTGS2SDHBDDR1S1PR1 | |
| SCHEMBL20393762 | 0.85 | — | — | |
| SCHEMBL20393635 | 0.84 | SDHB (0.46) | PTGS2PTGS1HPGDKDM4EGAA | |
| SCHEMBL20393710 | 0.84 | PTGS2 (0.42) | PTGS2PTGS1KCNH2 | |
| SCHEMBL20379045 | 0.83 | NPC1 (0.38) | PTGS2PTGS1KCNH2GRIN2BHPGD | |
| SCHEMBL30194787 | 0.83 | NPC1 (0.38) | PTGS2PTGS1KCNH2GRIN2BHPGD | |
| SCHEMBL20393870 | 0.83 | KCNH2 (0.34) | KCNH2KDM4EPOLBMAPTLMNA | |
| SCHEMBL21715798 | 0.83 | LMNA (0.37) | PTGS2KCNH2HPGDGAALMNA | |
| SCHEMBL20393624 | 0.83 | KCNH2 (0.31) | KCNH2HPGDLMNAHTTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11083199-B2 | Heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-08-10 | — | — | US | disclosed |
| US-20200045976-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| WO-2018130443-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11083199-B2 | Heterocycle derivatives as pesticides | DDT, CBR3, CBR1 | PTGS2 3487/4885PTGS1 3552/4885KCNH2 400/4885 |
| US-20200045976-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, CBR3, CBR1 | PTGS2 3487/4885PTGS1 3552/4885KCNH2 400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.