SCHEMBL20379487

SCHEMBL20379487

C=CC(=O)Nc1c(Br)c(Br)c(Br)c(Br)c1Br

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 12/20 0.50
▸ F13A1 P00488 1/20 0.50
▸ LMNA P02545 1/20 0.50
▸ TGM1 P22735 1/20 0.50
▸ TGM3 Q08188 1/20 0.50
▸ CYP2C19 P33261 1/20 0.37
▸ TSHR P16473 2/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ MAOA P21397 1/20 0.33
▸ MAOB P27338 1/20 0.33
▸ EGFR P00533 1/20 0.33
▸ PTPN1 P18031 1/20 0.33
▸ PTPN11 Q06124 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11179193 0.74 TGM2 (0.53) TGM2F13A1LMNATGM1TGM3
SCHEMBL5553620 0.71 TGM2 (0.50) TGM2F13A1LMNATGM1TGM3
SCHEMBL5480363 0.71 TGM2 (0.50) TGM2F13A1LMNATGM1TGM3
SCHEMBL31043510 0.70 TGM2 (0.42) TGM2F13A1LMNATGM1TGM3
SCHEMBL26026744 0.70 TGM2 (0.48) TGM2F13A1LMNATGM1TGM3
Acrylamide SCHEMBL28343508 0.69 TGM2 (0.47) TGM2F13A1LMNATGM1TGM3
SCHEMBL2723006 0.68 TGM2 (0.42) TGM2F13A1LMNATGM1TGM3
SCHEMBL5495518 0.67 TGM2 (0.50) TGM2F13A1LMNATGM1TGM3
SCHEMBL28741410 0.67 TGM2 (0.55) TGM2F13A1LMNATGM1TGM3
SCHEMBL9865216 0.67 TGM2 (0.68) TGM2F13A1LMNATGM1TGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 — — US disclosed
US-20190382519-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2019-12-19 — — US disclosed
WO-2018132548-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-07-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190382519-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ADSL, ABHD6, APH1B TGM2 1972/4885F13A1 1204/4885LMNA 2576/4885
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF PCNA, ADSL, APH1B TGM2 2386/4885F13A1 983/4885LMNA 2549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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