Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20380670 | 0.95 | PTGS2 (0.34) | AKR1C3AKR1C2PTGS2KDM1AAPP | |
| SCHEMBL20380738 | 0.91 | PTGS2 (0.33) | AKR1C3AKR1C2PTGS2KDM1AAPP | |
| SCHEMBL20380648 | 0.90 | — | — | |
| SCHEMBL20380579 | 0.90 | GPR3 (0.34) | HTR2ASLC6A4KCNH2PTGS2PTGS1 | |
| SCHEMBL20380655 | 0.90 | RPS6KA3 (0.32) | AKR1C3AKR1C2HTR2ASLC6A4KCNH2 | |
| SCHEMBL20380634 | 0.89 | GRM8 (0.32) | HTR2ASLC6A4KCNH2GPR3 | |
| SCHEMBL20380680 | 0.89 | FFAR4 (0.41) | — | |
| SCHEMBL20380646 | 0.89 | FFAR4 (0.41) | — | |
| SCHEMBL18887660 | 0.89 | AKR1C3 (0.33) | AKR1C3AKR1C2PTGS2PTGS1 | |
| SCHEMBL17367976 | 0.88 | PTGS2 (0.38) | AKR1C3AKR1C2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023799-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2018-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023799-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | PIEZO1, ROCK1, RCC1 | AKR1C3 3629/4885AKR1C2 3582/4885HTR2A 2769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.