Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437089 | 0.82 | TSHR (0.33) | TSHRLMNAALDH1A1SMN1; SMN2THRB | |
| SCHEMBL1899483 | 0.78 | ALDH1A1 (0.30) | TSHRLMNAALDH1A1 | |
| SCHEMBL1751456 | 0.78 | ALDH1A1 (0.30) | TSHRLMNAALDH1A1 | |
| SCHEMBL4333058 | 0.76 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| SCHEMBL28831243 | 0.76 | CES1 (0.36) | ALDH1A1 | |
| SCHEMBL28831186 | 0.76 | — | — | |
| SCHEMBL28831280 | 0.74 | — | — | |
| SCHEMBL392932 | 0.74 | EPHX1 (0.30) | — | |
| SCHEMBL3355262 | 0.74 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL28831185 | 0.74 | CES2 (0.39) | TSHRALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6667278-B2 | Include two bicyclic subunits each having vicinal diol group and polar unit and linked by linking moiety such that vicinal diol groups and polar unit are closely superimposable on corresponding functional groups in brassinosteroid | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2003-12-23 | — | — | US | claimed |
| US-20020115570-A1 | Non-steroidal mimetics of brassinolide | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2002-08-22 | — | — | US | claimed |
| WO-2002020694-A1 | LOW MOLECULAR CHROMOPHORE COMPOUNDS AND ELECTROLUMINESCENCE DISPLAY DEVICE COMPRISING THE SAME | VISTORM CO., LTD. (KR) | 2002-03-14 | — | — | WO | claimed |
| EP-0319900-B1 | FURYL, PHENYLENE AND THIENYL LEUKOTRIENE B4 ANALOGUES | G.D. Searle & Co. (US) | 1993-09-29 | — | — | EP | claimed |
| EP-0319900-A2 | Furyl, phenylene and thienyl leukotriene B4 analogues | G.D. Searle & Co. (US) | 1989-06-14 | — | — | EP | claimed |
| EP-3626716-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2020-03-25 | — | — | EP | disclosed |
| US-9981955-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2018-05-29 | — | — | US | disclosed |
| EP-3309157-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| US-20170029408-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2017-02-02 | — | — | US | disclosed |
| US-9511056-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2016-12-06 | — | — | US | disclosed |
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |
| US-5932133-A | Ion conducting electrolyte material | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1999-08-03 | — | — | US | disclosed |
| WO-1999010365-A2 | 5',5'-LINKED OLIGOMERS HAVING ANTI-THROMBIN ACTIVITY | GILEAD SCIENCES, INC. (US) | 1999-03-04 | — | — | WO | disclosed |
| US-5756723-A | Metal-mediated cross-coupling with ring-metalated porphyrins | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-05-26 | — | — | US | disclosed |
| US-5493017-A | Ring-metalated porphyrins | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0695741-A1 | 7-THIAPROSTAGLANDINS AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1996-02-07 | — | — | EP | disclosed |
| US-5427766-A | For detection and localization of tumors in tissues having estrogen receptors | THE DOW CHEMICAL COMPANY (US) | 1995-06-27 | — | — | US | disclosed |
| US-5371199-A | Substituted porphyrins, porphyrin-containing polymers, and synthetic methods therefor | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0416069-A1 | NEW LEUCOTRIENE B 4 DERIVATIVES, A METHOD OF PREPARING THEM, AND THEIR USE AS DRUGS. | SCHERING AG (DE) | 1991-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029408-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | TSHR 4853/4885LMNA 1353/4885ALDH1A1 3957/4885 |
| US-20020115570-A1 | Non-steroidal mimetics of brassinolide | BRDT, BRD1, NR5A1 | TSHR 3248/4885LMNA 3937/4885ALDH1A1 4749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.