SCHEMBL3355262

SCHEMBL3355262

C=CC(=C)[Sn](CCCC)(CCCC)CCCC

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7397348 0.74 TSHR (0.33) TSHRALDH1A1HPGDZDHHC20ZDHHC2
SCHEMBL9464579 0.74 TSHR (0.42) TSHRALDH1A1HPGDZDHHC20ZDHHC2
SCHEMBL437089 0.74 TSHR (0.33) TSHRALDH1A1
SCHEMBL203812 0.74 TSHR (0.33) TSHRALDH1A1
SCHEMBL1751456 0.70 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL1899483 0.70 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL28831243 0.68 CES1 (0.36) ALDH1A1
SCHEMBL4333058 0.68 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL28831186 0.68
SCHEMBL28831185 0.67 CES2 (0.39) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7173228-A None JP disclosed
JP-7268131-A None JP disclosed
US-10584187-B2 Initiators for the copolymerisation of diene monomers and vinyl aromatic monomers SYNTHOS S.A. (PL) 2020-03-10 US disclosed
EP-3280745-B1 INITIATORS FOR THE COPOLYMERISATION OF DIENE MONOMERS AND VINYL AROMATIC MONOMERS Synthos Sa (PL) 2018-12-12 EP disclosed
US-20180072821-A1 INITIATORS FOR THE COPOLYMERISATION OF DIENE MONOMERS AND VINYL AROMATIC MONOMERS SYNTHOS S.A. (PL) 2018-03-15 US disclosed
US-20140206793-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-24 US disclosed
US-20140187707-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-03 US disclosed
EP-2749591-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-07-02 EP disclosed
EP-2740759-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-06-11 EP disclosed
EP-2177562-B1 Polymer, rubber composition and tire using the same SUMITOMO RUBBER IND (JP) 2014-05-14 EP disclosed
US-20100099795-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
US-20100099810-A1 POLYMER, RUBBER COMPOSITION AND TIRE USING THE SAME SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-22 US disclosed
EP-2177562-A2 Polymer, rubber composition and tire using the same Sumitomo Rubber Industries, Ltd. (JP) 2010-04-21 EP disclosed
EP-1184412-B1 Rubber composition and heavy duty pneumetic tire using the rubber composition BRIDGESTONE CORP (JP) 2005-01-12 EP disclosed
US-6822027-B2 MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. BRIDGESTONE CORPORATION (JP) 2004-11-23 US disclosed
US-20020049294-A1 Rubber composition and heavy duty pneumatic tire using the rubber composition BRIDGESTONE CORPORATION 2002-04-25 US disclosed
EP-1184412-A1 Rubber composition and heavy duty pneumetic tire using the rubber composition Bridgestone Corporation (JP) 2002-03-06 EP disclosed
US-5508336-A LOW MOLECULAR WEIGHT AND HIGH MOLECULAR WEIGHT POLYMER COMPONENTS, EACH SELECTED FROM CONJUGATED DIENE POLYMER AND VINYLAROMATIC-CONJUGATED DIENE COPOLYMER, CARBON BLACK AND/OR WHITE CARBON BRIDGESTONE CORPORATION (JP) 1996-04-16 US disclosed
JP-H07268131-A RUBBER COMPOSITION BRIDGESTONE CORP 1995-10-17 JP disclosed
JP-H07173228-A COPOLYMER AND ITS PRODUCTION BRIDGESTONE CORP 1995-07-11 JP disclosed