Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321113 | 1.00 | LMNA (0.38) | LMNAEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL29351145 | 1.00 | LMNA (0.38) | LMNAEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL109627 | 0.89 | LMNA (0.37) | LMNAEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL20384698 | 0.89 | LMNA (0.37) | LMNAEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL29398201 | 0.89 | LMNA (0.37) | LMNAEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL23086185 | 0.88 | SMN1; SMN2 (0.41) | LMNAHPGDMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL30767122 | 0.88 | LMNA (0.36) | LMNAEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL11367709 | 0.87 | LMNA (0.39) | LMNAEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL22415048 | 0.85 | ALDH1A1 (0.35) | LMNAEHMT2EHMT1APOBEC3GHPGD | |
| SCHEMBL10340552 | 0.85 | LMNA (0.34) | LMNAEHMT2EHMT1APOBEC3GHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528527-B1 | Conjugates | ZENECA LTD (GB) | 1998-04-08 | — | — | EP | disclosed |
| EP-0528527-A2 | Conjugates | ZENECA LIMITED (GB) | 1993-02-24 | — | — | EP | disclosed |