Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385174 | 0.81 | SIGMAR1 (0.43) | HTTKCNN4SIGMAR1ALDH1A1BCAT2 | |
| SCHEMBL3383055 | 0.67 | HDAC1 (0.75) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL20385169 | 0.67 | SIGMAR1 (0.44) | HDAC1HDAC3SIGMAR1HSD17B10HDAC2 | |
| SCHEMBL20385115 | 0.66 | HTT (0.43) | HDAC1HDAC3HTTSIGMAR1ALDH1A1 | |
| SCHEMBL2459187 | 0.66 | ALDH1A1 (0.58) | MAPK13MAPK12MAPK11MAPK14HDAC1 | |
| Hydrogen Peroxide SCHEMBL27981905 | 0.64 | ALDH1A1 (0.94) | HTTALDH1A1HSD17B10HDAC2MAPK1 | |
| Hydrochloric Acid SCHEMBL20916299 | 0.63 | ALDH1A1 (0.54) | MAPK13MAPK12MAPK11MAPK14HDAC1 | |
| Hydrochloric Acid SCHEMBL30515278 | 0.63 | ALDH1A1 (0.54) | MAPK13MAPK12MAPK11MAPK14HDAC1 | |
| Anthranilic Acid SCHEMBL9173369 | 0.63 | BCAT2 (0.60) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL27783784 | 0.63 | MAPT (0.60) | MAPK13MAPK12MAPK11MAPK14HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |