Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17299437 | 0.84 | LIMK1 (0.41) | LIMK1PLA2G2APLA2G4AESR2ESR1 | |
| SCHEMBL18790515 | 0.82 | ESR2 (0.39) | PLA2G2APLA2G4AESR2ESR1PLA2G10 | |
| SCHEMBL19108890 | 0.82 | ALOX5 (0.41) | LIMK1PLA2G2APLA2G4AESR2PLA2G10 | |
| SCHEMBL24342903 | 0.82 | PLA2G2A (0.36) | LIMK1PLA2G2APLA2G4AESR2ESR1 | |
| SCHEMBL24341021 | 0.82 | LIMK1 (0.34) | LIMK1PLA2G2APLA2G4AESR2ESR1 | |
| SCHEMBL19108958 | 0.82 | PRKDC (0.39) | LIMK1ESR2ESR1ALOX5CDC14B | |
| SCHEMBL24342821 | 0.82 | ESR2 (0.39) | LIMK1ESR2ESR1ALOX5L3MBTL1 | |
| SCHEMBL19108955 | 0.81 | LIMK1 (0.39) | LIMK1PLA2G2APLA2G4AESR2ESR1 | |
| SCHEMBL1636254 | 0.81 | LIMK1 (0.45) | LIMK1PLA2G2APLA2G4AESR2ESR1 | |
| SCHEMBL24341019 | 0.81 | LIMK1 (0.41) | LIMK1PLA2G2APLA2G4AESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180205022-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2018-07-19 | — | — | US | disclosed |
| US-20180205022-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2018-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180205022-A1 | Organic Electroluminescent Materials and Devices | OCIAD2, OCIAD1, OPA1 | LIMK1 1000/4885PLA2G2A 2182/4885PLA2G4A 2999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.