SCHEMBL1636254

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1636884	0.91	LIMK1 (0.49)	LIMK1PLA2G2APLA2G4APIM3PIM1
	SCHEMBL9889883	0.87	LIMK1 (0.46)	LIMK1PLA2G2APLA2G4APIM3PIM1
	SCHEMBL17299437	0.87	LIMK1 (0.41)	LIMK1PLA2G2APLA2G4AESR2ESR1
	SCHEMBL17944365	0.87	ESR2 (0.41)	LIMK1PLA2G2APLA2G4AESR2ESR1
	SCHEMBL9889893	0.86	LIMK1 (0.45)	LIMK1PLA2G2APLA2G4APIM3PIM1
	SCHEMBL20821664	0.85	PLA2G2A (0.47)	LIMK1PLA2G2APLA2G4APIM3PLA2G10
	SCHEMBL19196039	0.85	LIMK1 (0.40)	LIMK1PLA2G2APLA2G4AESR2ESR1
	SCHEMBL18268559	0.84	ESR2 (0.41)	LIMK1PLA2G2APLA2G4AESR2ESR1
	SCHEMBL15043416	0.83	LIMK1 (0.41)	LIMK1PLA2G2APLA2G4APIM3PIM1
	SCHEMBL19081874	0.83	ESR2 (0.38)	LIMK1PLA2G2APLA2G4AESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.