Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.42 |
| ▸ | ACACA | Q13085 | 6/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | MST1R | Q04912 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16398857 | 0.78 | ACACB (0.47) | ACACBACACAJAK2NTRK1MET | |
| SCHEMBL12118986 | 0.73 | HSD17B1 (0.43) | ACACBACACAJAK2NTRK1MET | |
| SCHEMBL11940747 | 0.73 | ACACB (0.54) | ACACBACACAJAK2NTRK1MET | |
| SCHEMBL13273300 | 0.71 | ACACB (0.42) | ACACBACACAJAK2NTRK1MET | |
| SCHEMBL12119027 | 0.71 | HSD17B1 (0.38) | ACACBACACAJAK2NTRK1MET | |
| SCHEMBL12128964 | 0.69 | ACACB (0.46) | ACACBACACAJAK2NTRK1MET | |
| SCHEMBL11940679 | 0.68 | HSD17B1 (0.39) | ACACBACACAJAK2NTRK1MET | |
| SCHEMBL2355425 | 0.68 | ACACB (0.46) | ACACBACACAJAK2NTRK1MET | |
| SCHEMBL2355638 | 0.68 | ACACB (0.50) | ACACBACACAPGR | |
| SCHEMBL1025830 | 0.68 | PTGS2 (0.54) | HSD17B1PTGS1PTGS2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004063-B1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-07-18 | — | — | EP | disclosed |