Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.47 |
| ▸ | ACACA | Q13085 | 11/20 | 0.47 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | MST1R | Q04912 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12119027 | 0.84 | HSD17B1 (0.38) | ACACBACACAALKBH3JAK2NTRK1 | |
| SCHEMBL20392733 | 0.78 | ACACB (0.42) | ACACBACACAJAK2NTRK1MET | |
| SCHEMBL1160583 | 0.78 | MAPT (0.37) | TP53MAPTPTGS1PTGS2 | |
| SCHEMBL16398712 | 0.77 | S100A4 (0.34) | GSK3BPTGS1PTGS2 | |
| SCHEMBL16398123 | 0.76 | ERN1 (0.41) | PTGS1PTGS2 | |
| SCHEMBL16398521 | 0.74 | ACACB (0.44) | ACACBACACAALKBH3JAK2NTRK1 | |
| SCHEMBL11940747 | 0.73 | ACACB (0.54) | ACACBACACAJAK2NTRK1MET | |
| SCHEMBL16399022 | 0.73 | PTGS2 (0.42) | PTGS1PTGS2TDP2 | |
| SCHEMBL18971353 | 0.72 | ACACB (0.45) | ACACBACACAALKBH3JAK2NTRK1 | |
| SCHEMBL17012032 | 0.71 | ACACB (0.43) | ACACBACACAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10375956-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2019-08-13 | — | — | US | disclosed |
| US-10375956-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2019-08-13 | — | — | US | disclosed |
| EP-3004063-B1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-07-18 | — | — | EP | disclosed |
| EP-3004063-B1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-07-18 | — | — | EP | disclosed |
| US-20160128326-A1 | Herbicidally Active 2-(Substituted-Phenyl)-Cyclopentane-1,3-Dione Compounds and Derivatives Thereof | SYNGENTA LIMITED (GB) | 2016-05-12 | — | — | US | disclosed |
| US-20160128326-A1 | Herbicidally Active 2-(Substituted-Phenyl)-Cyclopentane-1,3-Dione Compounds and Derivatives Thereof | SYNGENTA LIMITED (GB) | 2016-05-12 | — | — | US | disclosed |
| EP-3004063-A1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | Syngenta Limited (GB) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014195327-A1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LIMITED (GB) | 2014-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160128326-A1 | Herbicidally Active 2-(Substituted-Phenyl)-Cyclopentane-1,3-Dione Compounds and Derivatives Thereof | DDT, HDHD5, CNPY2 | ACACB 3843/4885ACACA 3622/4885ALKBH3 118/4885 |
| US-10375956-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | DDT, HDHD5, CNPY2 | ACACB 3843/4885ACACA 3622/4885ALKBH3 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.